PIWIL1/piRNA-DQ593109 Regulates the Permeability of the Blood-Tumor Barrier via the MEG3/miR-330-5p/RUNX3 Axis

The blood-tumor barrier (BTB) restricts the efficient delivery of anti-glioma drugs to cranial glioma tissues.Increased BTB permeability may allow greater delivery of the therapeutic agents.Increasing evidence has revealed that PIWI susanne kaufmann vitamin c complex proteins and PIWI-interacting RNAs (piRNAs) play an important role in tumor progre

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Intra-periaqueductal Grey Matter Injection of Orexin A Attenuates Nitroglycerin-induced Deficits in Learning and Memory in Male Rats

This study explored the potential contribution of Orx1R within vlPAG to the learning and memory of animals with chronic migraine-like pain.Migraine was induced by repeated i.p.administration of nitroglycerin (5 mg/kg).Passive avoidance adeptness was evaluated in the shuttle box maze.The spatial memory performance was estimated using MWM tests.In th

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The Nagoya Protocol on Access to Genetic Resources and Benefit Sharing: What is New and What are the Implications for Provider and User Countries and the Scientific Community?

In culmination of the efforts by the Conference of the Parties (COP) of the Convention on Biological Diversity (1992) to adopt an international regime to regulate access and benefit sharing, the Nagoya Protocol was adopted at the COP 10 in Aichi-Nagoya, Japan, on 29 October 2010.The preceding negotiations aimed to produce a legal tool or regime tha

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